Report from a consensus conference on primary graft dysfunction after cardiac transplantation.
Identifieur interne : 003556 ( Main/Exploration ); précédent : 003555; suivant : 003557Report from a consensus conference on primary graft dysfunction after cardiac transplantation.
Auteurs : Jon Kobashigawa [États-Unis] ; Andreas Zuckermann [Autriche] ; Peter Macdonald [Australie] ; Pascal Leprince [France] ; Fardad Esmailian [États-Unis] ; Minh Luu [États-Unis] ; Donna Mancini [États-Unis] ; Jignesh Patel [États-Unis] ; Rabia Razi [États-Unis] ; Hermann Reichenspurner [Allemagne] ; Stuart Russell [États-Unis] ; Javier Segovia [Espagne] ; Nicolas Smedira [États-Unis] ; Josef Stehlik [États-Unis] ; Florian Wagner [Allemagne]Source :
- The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [ 1557-3117 ] ; 2014.
Descripteurs français
- KwdFr :
- Analyse de survie, Communication interdisciplinaire, Complications postopératoires (), Complications postopératoires (diagnostic), Complications postopératoires (mortalité), Complications postopératoires (physiopathologie), Comportement coopératif, Dysfonction primaire du greffon (), Dysfonction primaire du greffon (diagnostic), Dysfonction primaire du greffon (mortalité), Dysfonction primaire du greffon (physiopathologie), Facteurs de risque, Humains, Lésion de reperfusion myocardique (), Lésion de reperfusion myocardique (diagnostic), Lésion de reperfusion myocardique (mortalité), Lésion de reperfusion myocardique (physiopathologie), Préconditionnement ischémique myocardique, Rejet du greffon (), Rejet du greffon (diagnostic), Rejet du greffon (mortalité), Rejet du greffon (physiopathologie), Réintervention, Transplantation cardiaque (mortalité).
- MESH :
- diagnostic : Complications postopératoires, Dysfonction primaire du greffon, Lésion de reperfusion myocardique, Rejet du greffon.
- mortalité : Complications postopératoires, Dysfonction primaire du greffon, Lésion de reperfusion myocardique, Rejet du greffon, Transplantation cardiaque.
- physiopathologie : Complications postopératoires, Dysfonction primaire du greffon, Lésion de reperfusion myocardique, Rejet du greffon.
- Analyse de survie, Communication interdisciplinaire, Complications postopératoires, Comportement coopératif, Dysfonction primaire du greffon, Facteurs de risque, Humains, Lésion de reperfusion myocardique, Préconditionnement ischémique myocardique, Rejet du greffon, Réintervention.
English descriptors
- KwdEn :
- Cooperative Behavior, Graft Rejection (diagnosis), Graft Rejection (mortality), Graft Rejection (physiopathology), Graft Rejection (therapy), Heart Transplantation (mortality), Humans, Interdisciplinary Communication, Ischemic Preconditioning, Myocardial, Myocardial Reperfusion Injury (diagnosis), Myocardial Reperfusion Injury (mortality), Myocardial Reperfusion Injury (physiopathology), Myocardial Reperfusion Injury (therapy), Postoperative Complications (diagnosis), Postoperative Complications (mortality), Postoperative Complications (physiopathology), Postoperative Complications (therapy), Primary Graft Dysfunction (diagnosis), Primary Graft Dysfunction (mortality), Primary Graft Dysfunction (physiopathology), Primary Graft Dysfunction (therapy), Reoperation, Risk Factors, Survival Analysis.
- MESH :
- diagnosis : Graft Rejection, Myocardial Reperfusion Injury, Postoperative Complications, Primary Graft Dysfunction.
- mortality : Graft Rejection, Heart Transplantation, Myocardial Reperfusion Injury, Postoperative Complications, Primary Graft Dysfunction.
- physiopathology : Graft Rejection, Myocardial Reperfusion Injury, Postoperative Complications, Primary Graft Dysfunction.
- therapy : Graft Rejection, Myocardial Reperfusion Injury, Postoperative Complications, Primary Graft Dysfunction.
- Cooperative Behavior, Humans, Interdisciplinary Communication, Ischemic Preconditioning, Myocardial, Reoperation, Risk Factors, Survival Analysis.
Abstract
Although primary graft dysfunction (PGD) is fairly common early after cardiac transplant, standardized schemes for diagnosis and treatment remain contentious. Most major cardiac transplant centers use different definitions and parameters of cardiac function. Thus, there is difficulty comparing published reports and no agreed protocol for management. A consensus conference was organized to better define, diagnose, and manage PGD. There were 71 participants (transplant cardiologists, surgeons, immunologists and pathologists), with vast clinical and published experience in PGD, representing 42 heart transplant centers worldwide. State-of-the-art PGD presentations occurred with subsequent breakout sessions planned in an attempt to reach consensus on various issues. Graft dysfunction will be classified into primary graft dysfunction (PGD) or secondary graft dysfunction where there is a discernible cause such as hyperacute rejection, pulmonary hypertension, or surgical complications. PGD must be diagnosed within 24 hours of completion of surgery. PGD is divided into PGD-left ventricle and PGD-right ventricle. PGD-left ventricle is categorized into mild, moderate, or severe grades depending on the level of cardiac function and the extent of inotrope and mechanical support required. Agreed risk factors for PGD include donor, recipient, and surgical procedural factors. Recommended management involves minimization of risk factors, gradual increase of inotropes, and use of mechanical circulatory support as needed. Retransplantation may be indicated if risk factors are minimal. With a standardized definition of PGD, there will be more consistent recognition of this phenomenon and treatment modalities will be more comparable. This should lead to better understanding of PGD and prevention/minimization of its adverse outcomes.
DOI: 10.1016/j.healun.2014.02.027
PubMed: 24661451
Affiliations:
- Allemagne, Australie, Autriche, Espagne, France, États-Unis
- Californie, Communauté de Madrid, Hambourg, Maryland, Ohio, Utah, Vienne (Autriche), État de New York, Île-de-France
- Hambourg, Madrid, Paris, Vienne (Autriche)
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 003832
- to stream PubMed, to step Curation: 003718
- to stream PubMed, to step Checkpoint: 003718
- to stream Ncbi, to step Merge: 001892
- to stream Ncbi, to step Curation: 001892
- to stream Ncbi, to step Checkpoint: 001892
- to stream Main, to step Merge: 003573
- to stream Main, to step Curation: 003556
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Report from a consensus conference on primary graft dysfunction after cardiac transplantation.</title><author><name sortKey="Kobashigawa, Jon" sort="Kobashigawa, Jon" uniqKey="Kobashigawa J" first="Jon" last="Kobashigawa">Jon Kobashigawa</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California. Electronic address: kobashigawaj@cshs.org.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Zuckermann, Andreas" sort="Zuckermann, Andreas" uniqKey="Zuckermann A" first="Andreas" last="Zuckermann">Andreas Zuckermann</name><affiliation wicri:level="3"><nlm:affiliation>Medical University of Vienna, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Medical University of Vienna, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Macdonald, Peter" sort="Macdonald, Peter" uniqKey="Macdonald P" first="Peter" last="Macdonald">Peter Macdonald</name><affiliation wicri:level="1"><nlm:affiliation>St. Vincent's Hospital, Sydney, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>St. Vincent's Hospital, Sydney, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Leprince, Pascal" sort="Leprince, Pascal" uniqKey="Leprince P" first="Pascal" last="Leprince">Pascal Leprince</name><affiliation wicri:level="3"><nlm:affiliation>Pierre et Marie Curie University La Pitie-Salpétrière Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Pierre et Marie Curie University La Pitie-Salpétrière Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Esmailian, Fardad" sort="Esmailian, Fardad" uniqKey="Esmailian F" first="Fardad" last="Esmailian">Fardad Esmailian</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Luu, Minh" sort="Luu, Minh" uniqKey="Luu M" first="Minh" last="Luu">Minh Luu</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Mancini, Donna" sort="Mancini, Donna" uniqKey="Mancini D" first="Donna" last="Mancini">Donna Mancini</name><affiliation wicri:level="2"><nlm:affiliation>Columbia University, New York, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Columbia University, New York</wicri:cityArea></affiliation></author><author><name sortKey="Patel, Jignesh" sort="Patel, Jignesh" uniqKey="Patel J" first="Jignesh" last="Patel">Jignesh Patel</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Razi, Rabia" sort="Razi, Rabia" uniqKey="Razi R" first="Rabia" last="Razi">Rabia Razi</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Reichenspurner, Hermann" sort="Reichenspurner, Hermann" uniqKey="Reichenspurner H" first="Hermann" last="Reichenspurner">Hermann Reichenspurner</name><affiliation wicri:level="3"><nlm:affiliation>University Heart Centre, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Heart Centre, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Russell, Stuart" sort="Russell, Stuart" uniqKey="Russell S" first="Stuart" last="Russell">Stuart Russell</name><affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins Hospital, Baltimore, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Johns Hopkins Hospital, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Segovia, Javier" sort="Segovia, Javier" uniqKey="Segovia J" first="Javier" last="Segovia">Javier Segovia</name><affiliation wicri:level="3"><nlm:affiliation>Hospital de Puerta De Hierro, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital de Puerta De Hierro, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Smedira, Nicolas" sort="Smedira, Nicolas" uniqKey="Smedira N" first="Nicolas" last="Smedira">Nicolas Smedira</name><affiliation wicri:level="2"><nlm:affiliation>Cleveland Clinic, Cleveland, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Stehlik, Josef" sort="Stehlik, Josef" uniqKey="Stehlik J" first="Josef" last="Stehlik">Josef Stehlik</name><affiliation wicri:level="2"><nlm:affiliation>University of Utah, Salt Lake City, Utah.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Utah</region></placeName><wicri:cityArea>University of Utah, Salt Lake City</wicri:cityArea></affiliation></author><author><name sortKey="Wagner, Florian" sort="Wagner, Florian" uniqKey="Wagner F" first="Florian" last="Wagner">Florian Wagner</name><affiliation wicri:level="3"><nlm:affiliation>University Heart Centre, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Heart Centre, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24661451</idno><idno type="pmid">24661451</idno><idno type="doi">10.1016/j.healun.2014.02.027</idno><idno type="wicri:Area/PubMed/Corpus">003832</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003832</idno><idno type="wicri:Area/PubMed/Curation">003718</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003718</idno><idno type="wicri:Area/PubMed/Checkpoint">003718</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003718</idno><idno type="wicri:Area/Ncbi/Merge">001892</idno><idno type="wicri:Area/Ncbi/Curation">001892</idno><idno type="wicri:Area/Ncbi/Checkpoint">001892</idno><idno type="wicri:Area/Main/Merge">003573</idno><idno type="wicri:Area/Main/Curation">003556</idno><idno type="wicri:Area/Main/Exploration">003556</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Report from a consensus conference on primary graft dysfunction after cardiac transplantation.</title><author><name sortKey="Kobashigawa, Jon" sort="Kobashigawa, Jon" uniqKey="Kobashigawa J" first="Jon" last="Kobashigawa">Jon Kobashigawa</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California. Electronic address: kobashigawaj@cshs.org.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Zuckermann, Andreas" sort="Zuckermann, Andreas" uniqKey="Zuckermann A" first="Andreas" last="Zuckermann">Andreas Zuckermann</name><affiliation wicri:level="3"><nlm:affiliation>Medical University of Vienna, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Medical University of Vienna, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Macdonald, Peter" sort="Macdonald, Peter" uniqKey="Macdonald P" first="Peter" last="Macdonald">Peter Macdonald</name><affiliation wicri:level="1"><nlm:affiliation>St. Vincent's Hospital, Sydney, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>St. Vincent's Hospital, Sydney, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Leprince, Pascal" sort="Leprince, Pascal" uniqKey="Leprince P" first="Pascal" last="Leprince">Pascal Leprince</name><affiliation wicri:level="3"><nlm:affiliation>Pierre et Marie Curie University La Pitie-Salpétrière Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Pierre et Marie Curie University La Pitie-Salpétrière Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Esmailian, Fardad" sort="Esmailian, Fardad" uniqKey="Esmailian F" first="Fardad" last="Esmailian">Fardad Esmailian</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Luu, Minh" sort="Luu, Minh" uniqKey="Luu M" first="Minh" last="Luu">Minh Luu</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Mancini, Donna" sort="Mancini, Donna" uniqKey="Mancini D" first="Donna" last="Mancini">Donna Mancini</name><affiliation wicri:level="2"><nlm:affiliation>Columbia University, New York, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Columbia University, New York</wicri:cityArea></affiliation></author><author><name sortKey="Patel, Jignesh" sort="Patel, Jignesh" uniqKey="Patel J" first="Jignesh" last="Patel">Jignesh Patel</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Razi, Rabia" sort="Razi, Rabia" uniqKey="Razi R" first="Rabia" last="Razi">Rabia Razi</name><affiliation wicri:level="2"><nlm:affiliation>Cedars-Sinai Heart Institute, Los Angeles, California.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Cedars-Sinai Heart Institute, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Reichenspurner, Hermann" sort="Reichenspurner, Hermann" uniqKey="Reichenspurner H" first="Hermann" last="Reichenspurner">Hermann Reichenspurner</name><affiliation wicri:level="3"><nlm:affiliation>University Heart Centre, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Heart Centre, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Russell, Stuart" sort="Russell, Stuart" uniqKey="Russell S" first="Stuart" last="Russell">Stuart Russell</name><affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins Hospital, Baltimore, Maryland.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Johns Hopkins Hospital, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Segovia, Javier" sort="Segovia, Javier" uniqKey="Segovia J" first="Javier" last="Segovia">Javier Segovia</name><affiliation wicri:level="3"><nlm:affiliation>Hospital de Puerta De Hierro, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital de Puerta De Hierro, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Smedira, Nicolas" sort="Smedira, Nicolas" uniqKey="Smedira N" first="Nicolas" last="Smedira">Nicolas Smedira</name><affiliation wicri:level="2"><nlm:affiliation>Cleveland Clinic, Cleveland, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Stehlik, Josef" sort="Stehlik, Josef" uniqKey="Stehlik J" first="Josef" last="Stehlik">Josef Stehlik</name><affiliation wicri:level="2"><nlm:affiliation>University of Utah, Salt Lake City, Utah.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Utah</region></placeName><wicri:cityArea>University of Utah, Salt Lake City</wicri:cityArea></affiliation></author><author><name sortKey="Wagner, Florian" sort="Wagner, Florian" uniqKey="Wagner F" first="Florian" last="Wagner">Florian Wagner</name><affiliation wicri:level="3"><nlm:affiliation>University Heart Centre, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Heart Centre, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author></analytic><series><title level="j">The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation</title><idno type="eISSN">1557-3117</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cooperative Behavior</term><term>Graft Rejection (diagnosis)</term><term>Graft Rejection (mortality)</term><term>Graft Rejection (physiopathology)</term><term>Graft Rejection (therapy)</term><term>Heart Transplantation (mortality)</term><term>Humans</term><term>Interdisciplinary Communication</term><term>Ischemic Preconditioning, Myocardial</term><term>Myocardial Reperfusion Injury (diagnosis)</term><term>Myocardial Reperfusion Injury (mortality)</term><term>Myocardial Reperfusion Injury (physiopathology)</term><term>Myocardial Reperfusion Injury (therapy)</term><term>Postoperative Complications (diagnosis)</term><term>Postoperative Complications (mortality)</term><term>Postoperative Complications (physiopathology)</term><term>Postoperative Complications (therapy)</term><term>Primary Graft Dysfunction (diagnosis)</term><term>Primary Graft Dysfunction (mortality)</term><term>Primary Graft Dysfunction (physiopathology)</term><term>Primary Graft Dysfunction (therapy)</term><term>Reoperation</term><term>Risk Factors</term><term>Survival Analysis</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Analyse de survie</term><term>Communication interdisciplinaire</term><term>Complications postopératoires ()</term><term>Complications postopératoires (diagnostic)</term><term>Complications postopératoires (mortalité)</term><term>Complications postopératoires (physiopathologie)</term><term>Comportement coopératif</term><term>Dysfonction primaire du greffon ()</term><term>Dysfonction primaire du greffon (diagnostic)</term><term>Dysfonction primaire du greffon (mortalité)</term><term>Dysfonction primaire du greffon (physiopathologie)</term><term>Facteurs de risque</term><term>Humains</term><term>Lésion de reperfusion myocardique ()</term><term>Lésion de reperfusion myocardique (diagnostic)</term><term>Lésion de reperfusion myocardique (mortalité)</term><term>Lésion de reperfusion myocardique (physiopathologie)</term><term>Préconditionnement ischémique myocardique</term><term>Rejet du greffon ()</term><term>Rejet du greffon (diagnostic)</term><term>Rejet du greffon (mortalité)</term><term>Rejet du greffon (physiopathologie)</term><term>Réintervention</term><term>Transplantation cardiaque (mortalité)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Graft Rejection</term><term>Myocardial Reperfusion Injury</term><term>Postoperative Complications</term><term>Primary Graft Dysfunction</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Complications postopératoires</term><term>Dysfonction primaire du greffon</term><term>Lésion de reperfusion myocardique</term><term>Rejet du greffon</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Graft Rejection</term><term>Heart Transplantation</term><term>Myocardial Reperfusion Injury</term><term>Postoperative Complications</term><term>Primary Graft Dysfunction</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Complications postopératoires</term><term>Dysfonction primaire du greffon</term><term>Lésion de reperfusion myocardique</term><term>Rejet du greffon</term><term>Transplantation cardiaque</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Complications postopératoires</term><term>Dysfonction primaire du greffon</term><term>Lésion de reperfusion myocardique</term><term>Rejet du greffon</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Graft Rejection</term><term>Myocardial Reperfusion Injury</term><term>Postoperative Complications</term><term>Primary Graft Dysfunction</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Graft Rejection</term><term>Myocardial Reperfusion Injury</term><term>Postoperative Complications</term><term>Primary Graft Dysfunction</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cooperative Behavior</term><term>Humans</term><term>Interdisciplinary Communication</term><term>Ischemic Preconditioning, Myocardial</term><term>Reoperation</term><term>Risk Factors</term><term>Survival Analysis</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de survie</term><term>Communication interdisciplinaire</term><term>Complications postopératoires</term><term>Comportement coopératif</term><term>Dysfonction primaire du greffon</term><term>Facteurs de risque</term><term>Humains</term><term>Lésion de reperfusion myocardique</term><term>Préconditionnement ischémique myocardique</term><term>Rejet du greffon</term><term>Réintervention</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Although primary graft dysfunction (PGD) is fairly common early after cardiac transplant, standardized schemes for diagnosis and treatment remain contentious. Most major cardiac transplant centers use different definitions and parameters of cardiac function. Thus, there is difficulty comparing published reports and no agreed protocol for management. A consensus conference was organized to better define, diagnose, and manage PGD. There were 71 participants (transplant cardiologists, surgeons, immunologists and pathologists), with vast clinical and published experience in PGD, representing 42 heart transplant centers worldwide. State-of-the-art PGD presentations occurred with subsequent breakout sessions planned in an attempt to reach consensus on various issues. Graft dysfunction will be classified into primary graft dysfunction (PGD) or secondary graft dysfunction where there is a discernible cause such as hyperacute rejection, pulmonary hypertension, or surgical complications. PGD must be diagnosed within 24 hours of completion of surgery. PGD is divided into PGD-left ventricle and PGD-right ventricle. PGD-left ventricle is categorized into mild, moderate, or severe grades depending on the level of cardiac function and the extent of inotrope and mechanical support required. Agreed risk factors for PGD include donor, recipient, and surgical procedural factors. Recommended management involves minimization of risk factors, gradual increase of inotropes, and use of mechanical circulatory support as needed. Retransplantation may be indicated if risk factors are minimal. With a standardized definition of PGD, there will be more consistent recognition of this phenomenon and treatment modalities will be more comparable. This should lead to better understanding of PGD and prevention/minimization of its adverse outcomes.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Espagne</li><li>France</li><li>États-Unis</li></country><region><li>Californie</li><li>Communauté de Madrid</li><li>Hambourg</li><li>Maryland</li><li>Ohio</li><li>Utah</li><li>Vienne (Autriche)</li><li>État de New York</li><li>Île-de-France</li></region><settlement><li>Hambourg</li><li>Madrid</li><li>Paris</li><li>Vienne (Autriche)</li></settlement></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Kobashigawa, Jon" sort="Kobashigawa, Jon" uniqKey="Kobashigawa J" first="Jon" last="Kobashigawa">Jon Kobashigawa</name></region><name sortKey="Esmailian, Fardad" sort="Esmailian, Fardad" uniqKey="Esmailian F" first="Fardad" last="Esmailian">Fardad Esmailian</name><name sortKey="Luu, Minh" sort="Luu, Minh" uniqKey="Luu M" first="Minh" last="Luu">Minh Luu</name><name sortKey="Mancini, Donna" sort="Mancini, Donna" uniqKey="Mancini D" first="Donna" last="Mancini">Donna Mancini</name><name sortKey="Patel, Jignesh" sort="Patel, Jignesh" uniqKey="Patel J" first="Jignesh" last="Patel">Jignesh Patel</name><name sortKey="Razi, Rabia" sort="Razi, Rabia" uniqKey="Razi R" first="Rabia" last="Razi">Rabia Razi</name><name sortKey="Russell, Stuart" sort="Russell, Stuart" uniqKey="Russell S" first="Stuart" last="Russell">Stuart Russell</name><name sortKey="Smedira, Nicolas" sort="Smedira, Nicolas" uniqKey="Smedira N" first="Nicolas" last="Smedira">Nicolas Smedira</name><name sortKey="Stehlik, Josef" sort="Stehlik, Josef" uniqKey="Stehlik J" first="Josef" last="Stehlik">Josef Stehlik</name></country><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Zuckermann, Andreas" sort="Zuckermann, Andreas" uniqKey="Zuckermann A" first="Andreas" last="Zuckermann">Andreas Zuckermann</name></region></country><country name="Australie"><noRegion><name sortKey="Macdonald, Peter" sort="Macdonald, Peter" uniqKey="Macdonald P" first="Peter" last="Macdonald">Peter Macdonald</name></noRegion></country><country name="France"><region name="Île-de-France"><name sortKey="Leprince, Pascal" sort="Leprince, Pascal" uniqKey="Leprince P" first="Pascal" last="Leprince">Pascal Leprince</name></region></country><country name="Allemagne"><region name="Hambourg"><name sortKey="Reichenspurner, Hermann" sort="Reichenspurner, Hermann" uniqKey="Reichenspurner H" first="Hermann" last="Reichenspurner">Hermann Reichenspurner</name></region><name sortKey="Wagner, Florian" sort="Wagner, Florian" uniqKey="Wagner F" first="Florian" last="Wagner">Florian Wagner</name></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Segovia, Javier" sort="Segovia, Javier" uniqKey="Segovia J" first="Javier" last="Segovia">Javier Segovia</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003556 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003556 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:24661451
|texte= Report from a consensus conference on primary graft dysfunction after cardiac transplantation.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24661451" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |